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抗不整脈薬の分類
https://doi.org/10.34429/00000883
https://doi.org/10.34429/000008834cf0f7b7-3d0f-41bd-9ee9-14b1c513f91c
名前 / ファイル | ライセンス | アクション |
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KJ00000560847.pdf (453.2 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||||
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公開日 | 2014-08-14 | |||||||
タイトル | ||||||||
言語 | ja | |||||||
タイトル | 抗不整脈薬の分類 | |||||||
言語 | ||||||||
言語 | jpn | |||||||
キーワード | ||||||||
言語 | ja | |||||||
主題Scheme | Other | |||||||
主題 | Caチャネル | |||||||
キーワード | ||||||||
言語 | ja | |||||||
主題Scheme | Other | |||||||
主題 | Naチャネル | |||||||
キーワード | ||||||||
言語 | ja | |||||||
主題Scheme | Other | |||||||
主題 | 抗不整脈薬 | |||||||
資源タイプ | ||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||
資源タイプ | departmental bulletin paper | |||||||
ID登録 | ||||||||
ID登録 | 10.34429/00000883 | |||||||
ID登録タイプ | JaLC | |||||||
タイトルヨミ | ||||||||
ja-Kana | ||||||||
コウ フセイミャク ヤク ノ ブンルイ | ||||||||
タイトル(別表記) | ||||||||
その他のタイトル | Classification of antiarrhythmic drugs | |||||||
言語 | en | |||||||
著者名 |
橋本, 敬太郎
× 橋本, 敬太郎
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著者名(別表記) | ||||||||
姓名 | Hashimoto, Keitaro(en) | |||||||
内容 | ||||||||
内容記述タイプ | Other | |||||||
内容記述 | Antiarrhythmic drugs have been classified by their electrophysiological effects on cardiac action potential or by their effectiveness on various arrhythmias. The famous Vaughan Wnliams' classification divides antiarrhythmic drugs into 4 classes. Class I drugs are Na channel inhibitors, such as local anesthetics, and include almost all effective drugs on tachyarrhythmias. Class 2 drugs are adrenergic β blockers. These drugs must suppress Ca channel indirectly through inhibitingβ receptors. Class 3 drugs pro1ong action potential duration without affecting the max dV/dt, which is a measure of the rapid Na current. Class 4 drugs are Ca channel blockers. This classification does not help in choosing the proper drugs for treatment of tachyarrhythmia, because all the clinically effective drugs belong to class 1. We classified antiarrhythmic drugs by their effectiveness on canine model arrhythmias, and found that some class l drugs are effective on coronary ligation, digitalis and adrenaline arrhythmias, whne others showed effectiveness only on digitalis and coronary ligation arrhythmia or digitalis arrhythmia. Class 2 and 4 drugs only suppressed adrenaline arrhythmias. The usefulness of our classification for choosing antiarrhythmic drugs clinicically needs to be evaluated. | |||||||
言語 | ja | |||||||
出版者 | ||||||||
言語 | ja | |||||||
出版者 | 山梨医科大学 | |||||||
ISSN | ||||||||
収録物識別子タイプ | ISSN | |||||||
収録物識別子 | 0910-5069 | |||||||
NCID | ||||||||
収録物識別子タイプ | NCID | |||||||
収録物識別子 | AN10032951 | |||||||
書誌情報 |
ja : 山梨医科大学紀要 en : Bulletin of Yamanashi Medical University 巻 1, p. 1-5, 発行日 1984 |
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著者版フラグ | ||||||||
出版タイプ | VoR | |||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |