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<Original Article> Assessment of Plasma Protein S Functional Activity and Antigen in Patients with Liver Cirrhosis
https://doi.org/10.34429/00003148
https://doi.org/10.34429/00003148b1a952a3-6565-43ce-8536-4fed746e1b04
名前 / ファイル | ライセンス | アクション |
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AN10044054_06_04_03.pdf (805.8 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2010-05-18 | |||||
タイトル | ||||||
タイトル | <Original Article> Assessment of Plasma Protein S Functional Activity and Antigen in Patients with Liver Cirrhosis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題 | Protein S functional activity | |||||
キーワード | ||||||
主題 | Total and free protein S antigen | |||||
キーワード | ||||||
主題 | Protein S bound to C4b binding protein | |||||
キーワード | ||||||
主題 | C4b binding protein | |||||
キーワード | ||||||
主題 | Liver cirrhosis | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
ID登録 | ||||||
ID登録 | 10.34429/00003148 | |||||
ID登録タイプ | JaLC | |||||
著者名 |
KOBAYASHI, Isao
× KOBAYASHI, Isao× HAMAOKA, Satomi× AMEMIYA, Norihiko× ENDO, Takeshi× TAMURA, Kohji× KUME, Shoji× AKABANE, Kenji× SUZUKI, Hiroshi |
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内容 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Protein S functional activity, free and total protein S antigen as well as C4b binding protein antigen were assayed in patients with liver cirrhosis and the amounts of free protein S and protein S bound to C4b binding protbin in normal subjects and in patients with liver cirrhosis were also calculated from the area of two-dimensional immunoelectrophoresis. Cholinesterase activity correlated well with total protein S, C4b binding protein and protein S bound to C4b binding protein but not with the functional activity of protein S nor with free protein S antigen. The ratio of free protein S to protein S bound to C4b binding protein was 68±3%; in normal subjects and 127±69% in patients with liver cirrhosis. C4b binding protein had an inverse correlation with the ratio of free protein S to protein S bound to C4b binding protein. From these data, we can conclude that protein S bound to C4b binding protein but not free protein S reflects the level of liver function of macromolecular synthesis in liver cirrhosis and that the binding condition between C4b binding protein and protein S in patients with liver cirrhosis is different from that in normal subjects. | |||||
出版者 | ||||||
出版者 | 山梨医科大学医学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0912-0025 | |||||
NCID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN10044054 | |||||
書誌情報 |
山梨医科大学雑誌 en : 山梨医科大学雑誌 巻 6, 号 4, p. 183-191, 発行日 1991 |
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著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 |