{"_buckets": {"deposit": "13b3cd76-6f3a-4d39-90c9-993abe5426c8"}, "_deposit": {"created_by": 5, "id": "3857", "owners": [5], "pid": {"revision_id": 0, "type": "depid", "value": "3857"}, "status": "published"}, "_oai": {"id": "oai:yamanashi.repo.nii.ac.jp:00003857", "sets": ["366"]}, "author_link": [], "item_10001_biblio_info_7": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2011", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "37", "bibliographicPageStart": "34", "bibliographicVolumeNumber": "24", "bibliographic_titles": [{"bibliographic_title": "山梨肺癌研究会会誌", "bibliographic_titleLang": "ja"}, {"bibliographic_title": "Journal of the Yamanashi Society for Lung Cancer", "bibliographic_titleLang": "en"}]}]}, "item_10001_creator_2": {"attribute_name": "著者名", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "宮澤, 正久", "creatorNameLang": "ja"}]}, {"creatorNames": 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"肺癌切除標本にてEGFR遺伝子変異検索を行った36例につき検討した。測定は手術検体のパラフィン包埋標本から薄切切片を作製し、高感度法(PNA-LNA PCR clamp法)を用いて行った。1例を除き測定可能であり測定成功率は97.2%であった。対象症例全体の遺伝子変異陽性率は51.4%(18/35)であり、女性、腺癌、非喫煙者における陽性率はそれぞれ77.8%、75.0%、82.4%と高率であった。BAC成分をもつ腺癌において陽性率100%、また、女性、腺癌、非喫煙者の3因子を満たした場合も陽性率100%であった。非腺癌の陽性例はなかった。EGFR遺伝子変異検査に切除標本を用いることは、確実に腫瘍組織を含んだ検体を提出することにより偽陰性をなくすという利点があり、術後再発時における治療法の適切な選択につなげられると考えられた。", "subitem_description_language": "ja", "subitem_description_type": "Other"}]}, "item_10001_identifier_registration": {"attribute_name": "ID登録", "attribute_value_mlt": [{"subitem_identifier_reg_text": "10.34429/00003850", "subitem_identifier_reg_type": "JaLC"}]}, "item_10001_publisher_8": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "山梨肺癌研究会", "subitem_publisher_language": "ja"}]}, "item_10001_source_id_11": {"attribute_name": "NCID", "attribute_value_mlt": [{"subitem_source_identifier": "AN10355815"}]}, "item_10001_source_id_9": {"attribute_name": "ISSN", "attribute_value_mlt": 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肺癌切除標本におけるEGFR遺伝子変異検索に関する検討
https://doi.org/10.34429/00003850
https://doi.org/10.34429/00003850