@article{oai:yamanashi.repo.nii.ac.jp:00003102, author = {TASAKA, Kachio and YOSHIDA, Katsuo and YAMADA, Mubeo and YANAI, Nobuya and NAKAJIMA, Yasuo}, issue = {3}, journal = {山梨医科大学雑誌, 山梨医科大学雑誌}, month = {}, note = {In order to study the pathogenesis of autoimmune disease, serum M-CSF levels were measured by soft agar method in autoimmune MRL/lpr, BXSB, C3H/lpr, C3H/gld, NZB/W F1 mice as well as control MRL/n, C3H/Hej, BALB/c mice. Circulating levels of M-CSF were higher in MRL/lpr, C3H/lpr and C3H/gld mice than control mice, indicating the contribution of the lpr and gld genes. The number of macrophage precursor cell in the spleen was also higher in MRD/lpr, mouse than MRL/n mouse. However, there were no differences in Ia-positive macrophages from the bone marrow or spleen between high M-CSF group and low M-CSF group.}, pages = {105--114}, title = { High Serum Level of Macrophage Colony-Stimulating Factor (M-CSF) in lpr and gld Autoimmune Mice}, volume = {9}, year = {1994} }