{"created":"2023-05-18T10:11:26.764223+00:00","id":3190,"links":{},"metadata":{"_buckets":{"deposit":"45159a66-b689-4e02-9312-24e6dac68c14"},"_deposit":{"created_by":1,"id":"3190","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"3190"},"status":"published"},"_oai":{"id":"oai:yamanashi.repo.nii.ac.jp:00003190","sets":["205:251:302"]},"author_link":["14994","14995","14993","14992"],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1990","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"103","bibliographicPageStart":"97","bibliographicVolumeNumber":"5","bibliographic_titles":[{"bibliographic_title":"山梨医科大学雑誌"},{"bibliographic_title":"山梨医科大学雑誌","bibliographic_titleLang":"en"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"OZAKI, Yukio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"OYAMA, Toshio"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"MATSUMOTO, Yuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"KUME, Shoji"}],"nameIdentifiers":[{}]}]},"item_10001_description_5":{"attribute_name":"内容","attribute_value_mlt":[{"subitem_description":"Of the five cytokines tested (tumor necrosis factor, interleukin 1, colony-stimulating factor, interferon alpha, beta, and gamma), only tumor necrosis factor (TNF) showed a potent stimulatory effect on acetyltransferase activity of human neutrophils. Acetyltransforase is a key enzyme for the production of platelet-activating factor. This potentiating effect of TNF was time- and dose-dependent and was effectively blocked by TNF antiserum. Intracellular Ca++ elevation, protein kinase C activation, and arachidonic acid metabolites appeared not to be involved in the TNF-induced potentiation of the acetyltransferase activity in neutrophils.","subitem_description_type":"Other"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.34429/00003183","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"山梨医科大学医学会"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN10044054","subitem_source_identifier_type":"NCID"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0912-0025","subitem_source_identifier_type":"ISSN"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-27"}],"displaytype":"detail","filename":"AN10044054_05_02_03.pdf","filesize":[{"value":"665.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN10044054_05_02_03.pdf","url":"https://yamanashi.repo.nii.ac.jp/record/3190/files/AN10044054_05_02_03.pdf"},"version_id":"a5bdf51d-dd9c-46b6-beff-0330e4ee31c9"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"platelet-activating factor"},{"subitem_subject":"tumor necrosis factor"},{"subitem_subject":"neutrophils"},{"subitem_subject":"cytokines"},{"subitem_subject":"acetyltransferase"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"<Original Article> Tumor Necrosis Factor Stimulates Acetyltransferase Activity of Human Neutrophils","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"<Original Article> Tumor Necrosis Factor Stimulates Acetyltransferase Activity of Human Neutrophils"}]},"item_type_id":"10001","owner":"1","path":["302"],"pubdate":{"attribute_name":"公開日","attribute_value":"2010-11-09"},"publish_date":"2010-11-09","publish_status":"0","recid":"3190","relation_version_is_last":true,"title":["<Original Article> Tumor Necrosis Factor Stimulates Acetyltransferase Activity of Human Neutrophils"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-10-11T07:41:26.556718+00:00"}