{"created":"2023-05-18T10:12:48.380503+00:00","id":4843,"links":{},"metadata":{"_buckets":{"deposit":"9bdd4cc4-1b5c-4838-bacf-9cc360cca237"},"_deposit":{"created_by":5,"id":"4843","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"4843"},"status":"published"},"_oai":{"id":"oai:yamanashi.repo.nii.ac.jp:00004843","sets":["205:357:472"]},"author_link":[],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"13","bibliographicPageStart":"10","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"山梨肺癌研究会会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of the Yamanashi Society for Lung Cancer","bibliographic_titleLang":"en"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"熊谷, 隆","creatorNameLang":"ja"},{"creatorName":"クマガヤ, タカシ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"猪股, 紀江","creatorNameLang":"ja"},{"creatorName":"イノマタ, ノリエ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"小林, 寛明","creatorNameLang":"ja"},{"creatorName":"コバヤシ, ヒロアキ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"筒井, 俊晴","creatorNameLang":"ja"},{"creatorName":"ツツイ, トシハル","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"柿﨑, 有美子","creatorNameLang":"ja"},{"creatorName":"カキザキ, ユミコ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"宮下, 義啓","creatorNameLang":"ja"},{"creatorName":"ミヤシタ, ヨシタカ","creatorNameLang":"ja-Kana"}]}]},"item_10001_description_5":{"attribute_name":"内容","attribute_value_mlt":[{"subitem_description":"症例は84歳、女性。3か月前に左上葉肺腺癌に対して、左上葉切除術+リンパ節郭清術を施行されpT１cN2MO　StageⅢAの診断となった。手術検体でROS1融合遺伝子が確認されていた。呼吸困難を主訴に当院を受診し、胸部CTで両側に散在するすりガラス影と低酸素血症を認めた。造影CTで肺腺癌のリンパ節再発があり、凝固異常と心臓超音波検査で右心負荷・肺高血圧症を認めた。入院1週間で呼吸不全が急速に増悪しネーザルハイフロー管理が必要となった。臨床的に腫瘍塞栓性肺微小血管障害(PTTM)を疑い、Crizotinibによる肺癌治療を開始した。その後凝固異常・肺高血圧症は改善し第60病日には自宅退院した。今回の症例はPTTMにおける分子標的薬の有効性が示唆された。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.34429/00004825","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":" 山梨肺癌研究会 ","subitem_publisher_language":"ja"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN10355815"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-7053"}]},"item_10001_text_4":{"attribute_name":"タイトルヨミ","attribute_value_mlt":[{"subitem_text_language":"ja-Kana","subitem_text_value":"シュヨウ　ソクセンセイ　ハイ　ビショウ　ケッカン　ショウガイ　ガ　ウタガワレタ　ROS1 ユウゴウ　イデンシ　ヨウセイ　ハイセンガン　ノ　イチレイ"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-08-14"}],"displaytype":"detail","filename":"haigan33-1-010to013.pdf","filesize":[{"value":"790.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"haigan33-1-010to013","objectType":"fulltext","url":"https://yamanashi.repo.nii.ac.jp/record/4843/files/haigan33-1-010to013.pdf"},"version_id":"87416207-b3cd-40b9-8c18-57d31def16db"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"腫瘍塞栓性肺微小血管障害(PTTM)","subitem_subject_language":"ja"},{"subitem_subject":"ROS1融合遺伝子","subitem_subject_language":"ja"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"腫瘍塞栓性肺微小血管障害が疑われたROS1融合遺伝子陽性肺腺癌の一例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"腫瘍塞栓性肺微小血管障害が疑われたROS1融合遺伝子陽性肺腺癌の一例","subitem_title_language":"ja"}]},"item_type_id":"10001","owner":"5","path":["472"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-08-14"},"publish_date":"2020-08-14","publish_status":"0","recid":"4843","relation_version_is_last":true,"title":["腫瘍塞栓性肺微小血管障害が疑われたROS1融合遺伝子陽性肺腺癌の一例"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-10-11T07:46:51.294496+00:00"}