{"created":"2023-05-18T10:12:48.444453+00:00","id":4844,"links":{},"metadata":{"_buckets":{"deposit":"f22ba316-d9c3-4aec-92c7-e7796ca85eef"},"_deposit":{"created_by":5,"id":"4844","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"4844"},"status":"published"},"_oai":{"id":"oai:yamanashi.repo.nii.ac.jp:00004844","sets":["205:357:472"]},"author_link":[],"item_10001_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2020","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"18","bibliographicPageStart":"14","bibliographicVolumeNumber":"33","bibliographic_titles":[{"bibliographic_title":"山梨肺癌研究会会誌","bibliographic_titleLang":"ja"},{"bibliographic_title":"Journal of the Yamanashi Society for Lung Cancer","bibliographic_titleLang":"en"}]}]},"item_10001_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"樋田, 和弘","creatorNameLang":"ja"},{"creatorName":"トイタ, カズヒロ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"島村, 壮","creatorNameLang":"ja"},{"creatorName":"シマムラ, ソウ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"大越, 広貴","creatorNameLang":"ja"},{"creatorName":"オオゴシ, ヒロキ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"大木, 善之助","creatorNameLang":"ja"},{"creatorName":"オオキ, ゼンノスケ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"小澤, 克良","creatorNameLang":"ja"},{"creatorName":"オザワ, カツラ","creatorNameLang":"ja-Kana"}]},{"creatorNames":[{"creatorName":"菱山, 千祐","creatorNameLang":"ja"},{"creatorName":"ヒシヤマ, センスケ","creatorNameLang":"ja-Kana"}]}]},"item_10001_description_5":{"attribute_name":"内容","attribute_value_mlt":[{"subitem_description":"：症例は70歳代男性、上皮型悪性胸膜中皮腫stageⅢ に対し一次治療シスプラチン+ペメトレキセドを5コース、二次治療ビノレルビンを9コースまで行ったがいずれも腫瘍の増大を認めた。三次治療としてニボルマブを導入し腫瘍の縮小を得られた。ニボルマブ18回目投与後にgrade3(CTCAE version5.0)の耐糖能異常を認め休薬とした。耐糖能異常改善後も本人の希望でニボルマブを休止とし、最終投与後2カ月の時点で腫瘍縮小維持している。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_10001_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.34429/00004826","subitem_identifier_reg_type":"JaLC"}]},"item_10001_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"山梨肺癌研究会","subitem_publisher_language":"ja"}]},"item_10001_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN10355815"}]},"item_10001_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1341-7053"}]},"item_10001_text_4":{"attribute_name":"タイトルヨミ","attribute_value_mlt":[{"subitem_text_language":"ja-Kana","subitem_text_value":"ニボルマブ　ガ　ソウコウ　シタ　アクセイ　キョウマク　チュウヒシュ　ノ　イチレイ"}]},"item_10001_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-08-14"}],"displaytype":"detail","filename":"haigan33-1-014to018.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"haigan33-1-014to018","objectType":"fulltext","url":"https://yamanashi.repo.nii.ac.jp/record/4844/files/haigan33-1-014to018.pdf"},"version_id":"3ed6f5db-fa4c-46df-bfb5-2d24aa538d26"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"悪性胸膜中皮腫","subitem_subject_language":"ja"},{"subitem_subject":"ニボルマブ","subitem_subject_language":"ja"},{"subitem_subject":"免疫チェックポイント阻害薬","subitem_subject_language":"ja"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ニボルマブが奏効した悪性胸膜中皮腫の一例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ニボルマブが奏効した悪性胸膜中皮腫の一例","subitem_title_language":"ja"}]},"item_type_id":"10001","owner":"5","path":["472"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2020-08-14"},"publish_date":"2020-08-14","publish_status":"0","recid":"4844","relation_version_is_last":true,"title":["ニボルマブが奏効した悪性胸膜中皮腫の一例"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-10-11T07:46:54.987518+00:00"}