@article{oai:yamanashi.repo.nii.ac.jp:00000754,
 author = {宮坂, 芳明 and 石川, 徹 and 飯野, 弥 and 藤井, 秀樹 and 関川, 敬義 and 松本, 由朗},
 journal = {山梨医科大学紀要, Bulletin of Yamanashi Medical University},
 month = {},
 note = {The process of invasion and metastasis of carcinoma is compex and require a series of sequential steps. First step is the degradation of the extracellular matrix to allow the spreading of the carcinoma cells. We consider that a correlation between carcinoma cell and extracellular matrix is very important for this step. the maetalloproteinase play a major role in this step. Recently, MMP-2 and MMP-9/type IV collagenases/gelatinases are remarkable for carcinoma invasion and matastasis. We summerize the matrix metalloprotenase family and report our studies.},
 pages = {6--8},
 title = {大腸癌局所浸潤と間質反応:マトリックスメタロプロティナーゼ(MMP)について},
 volume = {14},
 year = {1997}
}