{"created":"2023-05-18T10:09:22.028446+00:00","id":754,"links":{},"metadata":{"_buckets":{"deposit":"813d5af9-e4bb-4ab1-8071-20205df28244"},"_deposit":{"created_by":5,"id":"754","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"754"},"status":"published"},"_oai":{"id":"oai:yamanashi.repo.nii.ac.jp:00000754","sets":["63:98:104"]},"author_link":["4426","4427","4428","4429","4430","4431"],"item_2_alternative_title_1":{"attribute_name":"タイトル(別表記)","attribute_value_mlt":[{"subitem_alternative_title":"The role of stroma in invasive region of human advanced colorectal cancer","subitem_alternative_title_language":"en"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1997","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"8","bibliographicPageStart":"6","bibliographicVolumeNumber":"14","bibliographic_titles":[{"bibliographic_title":"山梨医科大学紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Bulletin of Yamanashi Medical University","bibliographic_titleLang":"en"}]}]},"item_2_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"宮坂, 芳明","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"石川, 徹","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"飯野, 弥","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"藤井, 秀樹","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"関川, 敬義","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"松本, 由朗","creatorNameLang":"ja"}]}]},"item_2_description_5":{"attribute_name":"内容","attribute_value_mlt":[{"subitem_description":"The process of invasion and metastasis of carcinoma is compex and require a series of sequential steps. First step is the degradation of the extracellular matrix to allow the spreading of the carcinoma cells. We consider that a correlation between carcinoma cell and extracellular matrix is very important for this step. the maetalloproteinase play a major role in this step. Recently, MMP-2 and MMP-9/type IV collagenases/gelatinases are remarkable for carcinoma invasion and matastasis. We summerize the matrix metalloprotenase family and report our studies.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_2_full_name_24":{"attribute_name":"著者名(別表記)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"4426","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Miyasaka, Yoshiaki","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"4427","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ishikawa, Toru","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"4428","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Iino, Hiroshi","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"4429","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Fujii, Hideki","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"4430","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sekikawa, Takayoshi","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"4431","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Matsumoto, Yoshiro","nameLang":"en"}]}]},"item_2_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.34429/00000747","subitem_identifier_reg_type":"JaLC"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"山梨医科大学","subitem_publisher_language":"ja"}]},"item_2_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN10032951","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0910-5069","subitem_source_identifier_type":"ISSN"}]},"item_2_text_4":{"attribute_name":"タイトルヨミ","attribute_value_mlt":[{"subitem_text_language":"ja-Kana","subitem_text_value":"ダイチョウ ガン キョクショ シンジュン ト カンシツ ハンノウ マトリックス メタロ プロティナーゼ (MMP) ニツイテ"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-27"}],"displaytype":"detail","filename":"KJ00000560901.pdf","filesize":[{"value":"790.7 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000560901.pdf","objectType":"fulltext","url":"https://yamanashi.repo.nii.ac.jp/record/754/files/KJ00000560901.pdf"},"version_id":"16743ebb-c38c-4868-bf72-281db50082aa"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Matrix matalloproteinase","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"炎症細胞","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"局所浸潤","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"CD44","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト大腸癌","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"大腸癌局所浸潤と間質反応:マトリックスメタロプロティナーゼ(MMP)について","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"大腸癌局所浸潤と間質反応:マトリックスメタロプロティナーゼ(MMP)について","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"5","path":["104"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-08-21"},"publish_date":"2014-08-21","publish_status":"0","recid":"754","relation_version_is_last":true,"title":["大腸癌局所浸潤と間質反応:マトリックスメタロプロティナーゼ(MMP)について"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-10-11T06:50:59.951586+00:00"}