@article{oai:yamanashi.repo.nii.ac.jp:00000840, author = {Tasaka, Kachio and Sakihama, Toshiko and Iwamoto, Masahiro and Akasu, Fumito and Onaya, Toshimasa and Shirakura-Shibata, Yuri and Matsuda, Shunji and Nakajima, Yasuo}, journal = {山梨医科大学紀要, Bulletin of Yamanashi Medical University}, month = {}, note = {The major function of immunoglobulins (Igs) that is widely known is recognition and binding of specific antigens. In addition to this, they have other biological functions such as activation of complement, aggregation of platelets, and degranulation of basophils and mast cells. A new function of Ig was detected in an autoimmune mouse model, the induction of growth factor (s) from the FDC-P2/l85-4 cell line and stimulation of cell proliferation via an autocrine mechanism. Such a function of immunoglobulins might play an important role in the pathogenesis of autoimmune diseases.}, pages = {8--14}, title = {A new function of immunoglobulin : induction of a cytokine by IgG molecule from autoimmune mouse}, volume = {6}, year = {1989} }