{"created":"2023-05-18T10:09:27.787767+00:00","id":870,"links":{},"metadata":{"_buckets":{"deposit":"9ee1bd00-63b5-4dbf-a504-50b268d22b88"},"_deposit":{"created_by":5,"id":"870","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"870"},"status":"published"},"_oai":{"id":"oai:yamanashi.repo.nii.ac.jp:00000870","sets":["63:98:115"]},"author_link":["5049"],"item_2_alternative_title_1":{"attribute_name":"タイトル(別表記)","attribute_value_mlt":[{"subitem_alternative_title":"Problems in aging research : homeostasis and aging","subitem_alternative_title_language":"en"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1986","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"3","bibliographic_titles":[{"bibliographic_title":"山梨医科大学紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Bulletin of Yamanashi Medical University","bibliographic_titleLang":"en"}]}]},"item_2_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"入来, 正躬","creatorNameLang":"ja"}]}]},"item_2_description_5":{"attribute_name":"内容","attribute_value_mlt":[{"subitem_description":"I investigated the problems concerning homeostasis and aging, taking the regulations of body fluid and body temperature as an example. Homeostasis at rest is well maintained until an advanced age. However, in the aged, homeostasis is readily disturbed under various loads. Such disturbance of homeostasis can impair cell functions. The regulatory systems concerning homeostasis involve feed-back systems. It is also necessary to aging research to consider, 1) what is being regulated and how it is regulated, and 2) what interaction and hierarchy exist among regulatory systems. From this consideration, one of the characteristic changes due to aging, i.e. the combination of the decrease of certain functions and the resulting compensation, can be more precisely clarified. This combination over a long period is one of the important causes of l) the difficulty in evaluating the relationship between cell aging and the aging of the individual, 2) the discrepancies between the changes of structures and functions, and 3) larger individual differences observed in structural and functional changes of the aged.","subitem_description_language":"en","subitem_description_type":"Other"}]},"item_2_full_name_24":{"attribute_name":"著者名(別表記)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"5049","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Iriki, Masami","nameLang":"en"}]}]},"item_2_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.34429/00000863","subitem_identifier_reg_type":"JaLC"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"山梨医科大学","subitem_publisher_language":"ja"}]},"item_2_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN10032951","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0910-5069","subitem_source_identifier_type":"ISSN"}]},"item_2_text_4":{"attribute_name":"タイトルヨミ","attribute_value_mlt":[{"subitem_text_language":"ja-Kana","subitem_text_value":"ロウカ ケンキュウ コウ : ホメオスタシス ト ロウカ"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-27"}],"displaytype":"detail","filename":"KJ00000561001.pdf","filesize":[{"value":"567.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000561001.pdf","objectType":"fulltext","url":"https://yamanashi.repo.nii.ac.jp/record/870/files/KJ00000561001.pdf"},"version_id":"d9be1860-2e18-4989-a810-70837b119540"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"体液","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ホメオスタシス調節系","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"老化","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"ホメオスタシス","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"体温","subitem_subject_language":"ja","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"老化研究考 : ホメオスタシスと老化","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"老化研究考 : ホメオスタシスと老化","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"5","path":["115"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-08-14"},"publish_date":"2014-08-14","publish_status":"0","recid":"870","relation_version_is_last":true,"title":["老化研究考 : ホメオスタシスと老化"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-10-11T06:55:03.825680+00:00"}