{"created":"2023-05-18T10:09:28.052520+00:00","id":874,"links":{},"metadata":{"_buckets":{"deposit":"2f835d23-1719-4699-8e4a-55fae1b23fbb"},"_deposit":{"created_by":5,"id":"874","owners":[5],"pid":{"revision_id":0,"type":"depid","value":"874"},"status":"published"},"_oai":{"id":"oai:yamanashi.repo.nii.ac.jp:00000874","sets":["63:98:115"]},"author_link":["5074","5075"],"item_2_alternative_title_1":{"attribute_name":"タイトル(別表記)","attribute_value_mlt":[{"subitem_alternative_title":"Combination chemotherapy with cisplatin and methotrexate for advanced urothelial cancer","subitem_alternative_title_language":"en"}]},"item_2_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1986","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"31","bibliographicPageStart":"26","bibliographicVolumeNumber":"3","bibliographic_titles":[{"bibliographic_title":"山梨医科大学紀要","bibliographic_titleLang":"ja"},{"bibliographic_title":"Bulletin of Yamanashi Medical University","bibliographic_titleLang":"en"}]}]},"item_2_creator_2":{"attribute_name":"著者名","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小松, 秀樹","creatorNameLang":"ja"}]},{"creatorNames":[{"creatorName":"上野, 精","creatorNameLang":"ja"}]}]},"item_2_description_5":{"attribute_name":"内容","attribute_value_mlt":[{"subitem_description":"6例の進行尿路上皮癌患者に対し cisplatin(CDDP)、 methotrexate(MTX) 併用療法を施行した。対象は遠隔転移4例、傍大動脈リンパ節転移1例、局所進展1例の計6例である。CDDPは3週間に1回第1日目に70mg/M^2を点滴静注した。MTXは40mg/M2を3週間に2回、第1、第8日目に点滴静注した。以上を1コースとし、3-4コースを目標とした。奏効率は50%であった。CRは2例(33%)に得られた。肺、リンパ節、局所病変には有効であったが、骨転移には全く効果がなかった。かなり強い骨髄抑制がみられた。肺転移を有した1例は3コース終了後血小板数数13,000/mm3、白血球数300/mm3となり、肺炎を併発して死亡した。強い口内炎がみられたがこれはMTX 投与日、終日氷で口腔内を冷却することにより軽減できた。一過性の軽度の腎障害がみられたが、治療遂行の障害とはならなかった。","subitem_description_language":"ja","subitem_description_type":"Other"}]},"item_2_full_name_24":{"attribute_name":"著者名(別表記)","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"5074","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Komatsu, Hideki","nameLang":"en"}]},{"nameIdentifiers":[{"nameIdentifier":"5075","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Ueno, Akira","nameLang":"en"}]}]},"item_2_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.34429/00000867","subitem_identifier_reg_type":"JaLC"}]},"item_2_publisher_8":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"山梨医科大学","subitem_publisher_language":"ja"}]},"item_2_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN10032951","subitem_source_identifier_type":"NCID"}]},"item_2_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0910-5069","subitem_source_identifier_type":"ISSN"}]},"item_2_text_4":{"attribute_name":"タイトルヨミ","attribute_value_mlt":[{"subitem_text_language":"ja-Kana","subitem_text_value":"ニョウロ ジョウヒ ガン ニタイスル cisplatin, methotrexate ヘイヨウ リョウホウ"}]},"item_2_version_type_20":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-02-27"}],"displaytype":"detail","filename":"KJ00000561005.pdf","filesize":[{"value":"768.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KJ00000561005.pdf","objectType":"fulltext","url":"https://yamanashi.repo.nii.ac.jp/record/874/files/KJ00000561005.pdf"},"version_id":"1fda2de6-7982-449c-aa5d-2f51dbac4a8f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"尿路上皮癌に対するcisplatin,methotrexate併用療法","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"尿路上皮癌に対するcisplatin,methotrexate併用療法","subitem_title_language":"ja"}]},"item_type_id":"2","owner":"5","path":["115"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2014-08-14"},"publish_date":"2014-08-14","publish_status":"0","recid":"874","relation_version_is_last":true,"title":["尿路上皮癌に対するcisplatin,methotrexate併用療法"],"weko_creator_id":"5","weko_shared_id":-1},"updated":"2023-10-11T06:55:05.963915+00:00"}