| Item type |
紀要論文 / Departmental Bulletin Paper(1) |
| 公開日 |
2014-08-18 |
| タイトル |
|
|
タイトル |
老化にみられる遺伝因子 |
|
言語 |
ja |
| 言語 |
|
|
言語 |
jpn |
| キーワード |
|
|
言語 |
ja |
|
主題Scheme |
Other |
|
主題 |
大動脈脈波速度 |
| キーワード |
|
|
言語 |
ja |
|
主題Scheme |
Other |
|
主題 |
骨塩量 |
| キーワード |
|
|
言語 |
ja |
|
主題Scheme |
Other |
|
主題 |
双生児研究法 |
| キーワード |
|
|
言語 |
ja |
|
主題Scheme |
Other |
|
主題 |
血圧 |
| キーワード |
|
|
言語 |
ja |
|
主題Scheme |
Other |
|
主題 |
老化 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
departmental bulletin paper |
| ID登録 |
|
|
ID登録 |
10.34429/00000825 |
|
ID登録タイプ |
JaLC |
| タイトルヨミ |
|
|
|
ja-Kana |
|
|
ロウカ ニミラレル イデン インシ |
| タイトル(別表記) |
|
|
その他のタイトル |
Twin study method on genetic factors relating to aging. |
|
言語 |
en |
| 著者名 |
浅香, 昭雄
飯島, 純夫
竹下, 達也
山縣, 然太郎
木之下, 徹
|
| 著者名(別表記) |
|
|
|
識別子Scheme |
WEKO |
|
|
識別子 |
4891 |
|
|
姓名 |
Asaka, Akio(en) |
| 著者名(別表記) |
|
|
|
識別子Scheme |
WEKO |
|
|
識別子 |
4892 |
|
|
姓名 |
Iijima, Sumio(en) |
| 著者名(別表記) |
|
|
|
識別子Scheme |
WEKO |
|
|
識別子 |
4893 |
|
|
姓名 |
Takeshita, Tatsuya(en) |
| 著者名(別表記) |
|
|
|
識別子Scheme |
WEKO |
|
|
識別子 |
4894 |
|
|
姓名 |
Yamagata, Zentaro(en) |
| 著者名(別表記) |
|
|
|
識別子Scheme |
WEKO |
|
|
識別子 |
4895 |
|
|
姓名 |
Kinoshita, Toru(en) |
| 内容 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Subjects were monozygotic twins. Aortic pulse wave velocity (PWV), blood pressure (BP) and bone mineral density (BMD) were examined. It was revealed that PWV, BP and BMD were all strongly determined by genetic factors. It is well known that PWV or BMD is an excellent indicator of arteriosclerosis or osteoporosis, respectively. For the early detection or prevention of these diseases it is necessary to examine PWV or BMD. At the same time, it was shown that risk factors in the environment were effectively clarified by use of twin method. BP was said to be influenced by additive genes. However, the effect of non-additive genes or single gene may play an important role for the value of BP as well as for the manifestation of hypertension, due to the present study, that is, by the newly designed maximum likelihood method. Monozygotic twins concordant or discordant for Alzheimer disease in the literature were analysed. The result indicated the presence of genetic heterogeneity of Alzheimer disease. Therefore, the strategy for the clarification of the disease should be made by different way according to the different mode of inheritance. Molecular genetic study was persuaded to the group which is under genetic control of a single dominant gene. Another approach shoud be the investigation of the risk factors in the environment for the group, which is caused by the effects of multifactorial inheritance. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
山梨医科大学 |
|
言語 |
ja |
| ISSN |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0910-5069 |
| NCID |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10032951 |
| 書誌情報 |
ja : 山梨医科大学紀要
en : Bulletin of Yamanashi Medical University
巻 7,
p. 20-26,
発行日 1990
|
| 著者版フラグ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
KJ00000561044.pdf (593.3 kB)
